Comedian John Mulaney became the first comedian to perform at Wrigley Field, home of the Chicago Cubs, on Saturday night. Mulaney addressed a packed crowd, bringing along his famous friends for this historic evening. One of the surprises of the night was David Letterman taking the stage and thrilling the audience with the question, "How did this happen?" Letterman praised Mulaney's performance, stating, "This makes Taylor Swift's wedding look like a student film."

There were more surprises at this stop of Mulaney's Mister Whatever tour. Chicago blues legend Buddy Guy opened the show, and the 89-year-old artist gave a brief performance while the audience settled in. Guy continues to perform in cities like Toronto, New York, Michigan, Kansas, and Missouri this month.

The evening was hosted by Richard Kind, a long-time friend of Mulaney. Kind took the stage with a "Mayor" sash to introduce Mulaney's former Saturday Night Live colleague, Fred Armisen. Armisen entertained the audience with a comedy set that included musical numbers.

Finally, Letterman took on the task of inviting Mulaney to the stage. The two had spent time together recently; Mulaney had been a guest at Letterman's Netflix is a Joke Festival held at the Montalban Theatre in Hollywood in May. This special night was recorded as a significant milestone in Mulaney's career.