Ikki Igarashi's life turns to the bizarre when he starts seeing a demon who appeared from within his body.
Ikki refuses to continue using the Revice Driver as he insists on working at his family's sento and is afraid of Vice's desire to eat humans.
As the Igarashis face an eviction notice and the potential loss of their sento due to city renovations, Daiji visits his hospitalized mother, Yukimi, for advice.
Ikki successfully rescues Sakura and Ayaka from a Deadman, only to learn their kidnapper is not in possession of the corresponding Vistamp, forcing him and Vice to find it before it causes more trouble.
After Ikki officially joins Fenix, his father Genta takes advantage by establishing a project to garner subscribers.
In the hopes of identifying the mysterious Kamen Rider Evil, Ikki and his friends develop a strategy involving Bon.
While Ikki is dispatched to stop two of four thieves who became Phase 2 Deadmen, Kadota notices Daiji's sudden personality change.
To celebrate Yukimi being discharged from the hospital, the Igarashis take a trip to a hot spring resort. Upon arriving however, they learn that their regular customers, the Ushijima family, are also there.
After the Igarashi family discovers what happened to Daiji, Fenix orders Ikki to eliminate Kagero.
Despite learning that Kagero was spawned from Daiji's inferiority complex towards him, Ikki continues to fight in the hopes of reaching his brother.
Due to the increasing numbers of Deadmen-related crimes, people who receive Vistamps begin to use them in new ways.
After Sakura awakens her inner demon instead of becoming a Kamen Rider and Ikki is injured while protecting her, Daiji demands she hand over her Rider equipment to Fenix so they can investigate the person who sent them.
Fenix is forced to land their mobile headquarters, the Sky Base, in order to refuel, restock on supplies, and give several of their operatives, such as Kadota, time off.
Wakabayashi is suspected of being a traitor and the contract holder connected to the Chameleon Deadman. In spite of Daiji and Kadota's shock, Karizaki decides to set a trap for the Deadman to confirm.
A shocked Aguilera discovers she is intended to become a sacrifice for Giff's revival instead of his bride, which her right hand Orteca knew about and withheld from her while her bodyguard Julio becomes livid over the revelation.
Deadmans' attack has been thwarted, but Aguilera and Julio are on the run together while Orteca and the Chameleon Deadman move forward with their own plans.
Shortly after the Chameleon Deadman's demise and Kadota's promotion to commander, Karizaki discovers the truth behind Genta's condition.
Upon learning Deadmans can use the Giff Stamp to sacrifice humans and turn them into Gifftarian Deadmen, Ikki strengthens his resolve to avert Giff's revival.
After Kamen Rider Revice successfully masters the Volcano Rex Vistamp's power and develop the ability to separate Gifftex Deadmen from their human hosts while restoring Julio's humanity, Orteca grows worried over the latter prospect and begins to target Kadota.
After Yamagiri is revealed to be a traitor when she discovered dubious operations within Fenix, Kadota's condition grows worse as he starts hearing his Demons Driver telling him it will devour him.
Ikki and Vice rescue Kadota from the Demons Driver, but he chooses to resign from Fenix due to his fluctuating emotions and wavering loyalty to the organization; Fenix has captured Orteca, who has been separated from his Deadman form.
After losing Kadota to Orteca, Ikki buries himself in his sentô work to distance himself from the tragedy.
Following a mishap with the unsanctioned Rolling Vistamp, Ikki and Vice switch corporeal states. Overjoyed by his new state of being, the latter goes rogue to destroy the Vistamp and make the switch permanent.
Following Kagero's testimony regarding Fenix and Giff, George decides to investigate them once more while helping Ikki and Vice reverse the Rolling Vistamp's side effects.
Following Genta Igarashi's sudden transformation into Kamen Rider Vail, Igarashi siblings discovers they are Giff's descendants by birth through their father.
Following Genta Igarashi's sudden transformation into Kamen Rider Vail, the Igarashi siblings discover they are Giff's descendants through their father as their inner demons' connection to the original demon grows stronger.
Akaishi reveals Julio, Orteca, and Aguilera are test subjects used by Noah, a group of criminal scientists who seek to use Giff's cells to turn humans into demons, and that he has been using Fenix to transform its soldiers into demons.
As Giff's eerie awakening becomes stronger, it causes Vice to go berserk within Ikki's body and keep escaping from Weekend's custody easily.
Sometimes after Vice's rescue and Orteca's demise, George and the Igarashi siblings discover Kadota is alive, albeit suffering from amnesia.
While at his high school soccer club reunion, Ikki reunites with his former coach and mentor Subaru Kimura, who is now a famous voice actor.