Disguised a Western Union messenger, Willie Sutton (Jay Novello) tricks the janitor at a jewelry store on Broadway to open the door before the start of business. Sutton and an accomplice pull guns and prevent the janitor from warning the store manager when he arrives to open the store, and them force the manager to open the safe. The thieves make off with $130,000 in jewels, leaving a total of six hostages behind.

Three vicious hoods on a crime rampage take over a church mission as their headquarters, figuring the cops would never look for them there.

Police pursue John Dillinger and his henchman, Homer Van Meter across the Midwest. On the run, Van Meter digs up loot hidden in glass jars, but is double-crossed by one of his underlings.

John Dillinger, a notorious 1930s bank robber, escapes from the state penitentiary using a wooden gun, but makes a critical error when he crosses the state line in a stolen car. That act violated a U.S. law, causing the FBI to take up the hunt. Although Dillinger manages to escape from several traps set by the G-men, he's finally cornered by agents leaving a Chicago movie theater with "The Lady in Red".