Odyssey'nin yeni gemi doktoru Max Bankman, kıyıdan kilometrelerce uzakta yaşanan krizlerle ilgilenirken Kaptan Massey'yi ve onun sağlık ekibinden Avery'yi ve Tristan'ı tanır.

Max, Tristan ve Avery ilişkilerini yoluna koymaya çalışırken, ekip yolcuların yakınlaşma girişimlerini savuşturur. Artan istekler ve hızla yayılan rahatsızlıklardan dolayı Max ve ekibi düzeni geri getirmek için harekete geçer.

Kaptan Massey, geminin sahibinin karısının ona yaptığı hamleleri savuşturmak zorundadır.

Odyssey'ye hasta akını olur.

Zombi benzeri bir hastalık belli yolcuların başına bela olur.

Varlıklı bir aile, düğün seyahati için The Odyssey’yi kiralar.

Max, Avery ve Tristan ilişkilerine yön verir.

İlginç bir akım, kruvaziyer sektörünü kasıp kavurur.

Max and Avery are at a crossroads as Avery faces a difficult pregnancy decision. Meanwhile, after Munroe is bitten by a shark, the Odyssey takes a dangerous detour to rescue a sinking boat, where a mysterious new passenger catches Max's eye.

Amid a power outage, Max, Tristan, Avery, and Brooke struggle to treat shark-inflicted wounds. As romantic tensions flare between Max and Brooke and new sparks fly between two former flames, the team must perform an emergency operation.

It's Casino Week aboard The Odyssey, and unexpected guest Athena Grant suspects two passengers are targeting the ship's vault. Enlisting Max's help, Athena raises the stakes in a dangerous game where not everyone will end up with a winning hand.

Tristan strives to prove himself to Avery, while Captain Massey is shaken by shocking news. Meanwhile, Sophisticated Ladies Week brings a disruptive passenger onboard, while the crew navigates the delicate care of a terminal patient.

Spring break hits The Odyssey as three college "vixens" set their sights on Max. Meanwhile, Tristan faces his drinking problem while other passengers' struggles keep the medical team on their toes.

Cheerleaders aboard The Odyssey bring nostalgia, but when Avery receives troubling news, Max and Tristan step in to support her. Meanwhile, Tristan explores sobriety while Captain Massey's stress takes a physical toll.

Crew week on The Odyssey sends Max back to his hometown for answers, while Tristan reveals Avery's secret to Vivian. As Munroe fights a parasitic infection, Avery pressures Rosie to face a medical condition she's been hiding.

Mayhem ensues on The Odyssey when high-profile book tours for trad wives and sex-positive groups are double-booked. As tensions rise, Max, Avery and Tristan provide medical attention to both VIP authors.

After Max's declaration fractures his relationship with Avery, he leaves the ship and finds himself caught in an earthquake, which triggers a tsunami warning. With The Odyssey forced to leave port, Max races to return before it's too late.

When Max's transmission goes silent, he and Barry seek refuge in an abandoned church while Tristan takes charge of The Odyssey. With time running out, Avery leads a high-stakes rescue mission to find Max.