A man returning from Mexico requires emergency Narcan after a suspected opioid overdose; an unlikely family is caught trying to smuggle firearms into Mexico; a woman attempting to sneak prescription meds into the U.S. is caught red-handed.

A man who arrives at the border with a baby is concealing another valuable commodity; a couple who fails to declare Mexican avocados ends up causing a scene; a teenager claiming to be a U.S. citizen arrives looking to attend high school in Texas.

Following the work of America's Customs and Border Protection agency, whose job is to defend the border and stop terrorists, drugs and illegal weapons from entering the country.

The cartel tries to sneak one last shipment over the border just before midnight; officers uncover a delivery that isn't what it seems; a woman acting erratically is found with a Santa Muerte statue, indicating she may have cartel connections.

Methamphetamine is found hidden within a semi-truck full of frozen broccoli, a man is caught smuggling pills inside containers of protein powder, a traveler tries to bring a deer trophy across the border, and an intoxicated US citizen is detained.

A woman returning from a shopping trip in the US attempts to smuggle dirty money into Mexico; a van full of clothes is hiding an exotic shipment; a man finds a clever hiding place for prescription drugs; a family tries to bring in illicit fruits.

A drunk driver causes a three-car crash; a man attempts to import counterfeit goods; an investigation is launched into a pill-smuggling ring, and a shipment of cocaine is found inside office furniture; an armed robber on the run is captured.

Dirty cartel money is found hidden in a truck; an intoxicated minor requires medical treatment; a man tries to enter the US with a false visa, and two sisters are caught smuggling meds; a large quantity of cocaine is found hidden inside trash bags.

Officers stop a man suspected of money laundering. Cocaine is found hidden in an unexpected area of a shipping truck. A traveler is caught trying to bring weaponry into Mexico. A father is stopped when trying to smuggle medication for his son.

An illicit shipment is disguised in bags of concrete. Officers identify a criminal wanted for burglary when he attempts to cross the border. A woman is caught smuggling too many diet pills. A retired police officer almost carries a gun into Mexico.