An Indian outbreak threatens to erupt when Billy Blue Cannon and an Apache boy fight over a wild horse.

When John Cannon feeds hungry Apache children orphaned by Pima Indian attacks, his ranch is threatened by the two tribes.

Ranch foreman Sam Butler returns to his native border town to avenge the death of his daughter.

Buck Cannon's plans to open a saloon are threatened by a temperance group led by spirited Frances O'Tolle.

Mexican bandit El Lobo breaks jail and plots to plunder the Cannon Ranch supplies to avenge his imprisonment by Manolito.

Don Sebastian Montoya repudiates his promise to sell a small village on his land to tenants after Vaquero obtains the purchase money.

Crusading editor Ebenezer Binns risks his life against extortionists and killers.

When Victoria saves the life of a man injured in a stagecoach plundered by Comancheros, she learns the man has sworn to kill her husband.

Chio, an Apache half-breed and his renegades, capture Cannon's supply wagons. Just as food and ammunition for High Chaparral runs out, Chio is captured and brought to the ranch. Meanwhile, Manolito discovers Tina Granger near a burned out stage coach in an apparently unrelated incident. Tina, Chio's daughter, helps him to escape, but leaves her father when he vows to plunder the ranch to gain recognition. Feeling a loyalty to the Cannons who treated her well at the High Chaparral, she leads Buck and Manolito to the stolen supplies and joins them in a dash for the ranch pursued by Chio and his men.

""A factual drama based on the 10th Cavalry, a Negro regiment formed in 1866. Lawlessness in Tucson brings martial law--and the 10th--into open conflict with the town's white populace and an army of outlaws. Members of the honorary 10th Cavalry, formed in Los Angeles in 1966, are featured in this episode."" (TV Guide)

John Cannon quarrels with a neighbor and Indians, and interrupts Thanksgiving plans.

John Cannon is accused of killing the daughter of a Mexican sheepherder and is condemned to death unless steep ransom is paid.

Ricardo Montalban guest-stars as a priest who obtains money from the Cannon family, presumably to finance his search for a religious statue, but channels the funds to the poor.

An Army deserter accused of murder takes Billy Blue as hostage.

The celebration of a peace treaty with the Indians is cut short for the Cannons by scalp hunters disguised as lawmen.

Against John Cannon's advice, Mano helps Sean McLaren, an Irish miner, and his friends in their strike against dangerous working conditions.

Lucien Charot raises his freight prices by having Indian attacks faked against his wagons. John interests an El Paso stage and freight line in extending operations to Tucson with local merchants financing the plan. Charot increases the phony raids and the frightened merchants withdraw from the deal. John then puts his ranch up to guarantee the initial safety of the new line. Victoria joins John for the first ride into Tucson while Charot and his gunmen wait in ambush.

Manolito leaves the routine of the Cannon Ranch searching excitement and becomes involved with three uniformed musicians.

Billy is taken hostage by Apaches after he ignores Buck's advice and frees a white girl from them.

Victoria, feeling ignored, leaves her husband John but finds little peace of mind at her father's ranch.

A flamboyant Irishman cons Buck into buying a camel, promising it will revolutionize the cattle industry.

A dishonest Indian agent jeopardizes the future of an Apache reservation started by John Cannon.

Buck hires saddle tramp Orville Kilroy, who hides his criminal past and quickly becomes the most popular hand on the Cannon Ranch.

Buck tries to find and return the missing husband of Ann Simmons, an old girlfriend.

Don Sebastian, wounded by a would-be assassin, plays on the sympathy of his family and friends in a scheme to gain control of the Cannon Ranch.

Victoria reopens Tucson's only school and befriends a troubled Mexican boy, but is kidnapped by the boy's father.