The 14 girls all go to an interview with the press where they are asked why they want to win. Lisa is disappointed in Aaron, Leanne and Martha for not saying they think they can win, but says she is impressed and excited by Alex.

The girls are sent on a crash course in dance with top choreographer Supple. When Supple asks for them each to freestyle he is not impressed with the girls' moves and goes on to announce that only one person has a glimmer of potential, Leanne. The girls then get a runway lesson from top fashionista Jeanette who has the girls walk in seven inch platform stilettos designed by Terry De Havilland. Leanne, having done well in the previous task, breaks down into tears after falling flat on her face during the runway challenge.

The girls are told that they are getting their makeovers in a Lisa Mail. Once they arrive at the salon, they discover that all the mirrors have been covered with black paper - to prevent the girls from seeing their makeovers till they are completed. Aaron, Charlotte, Rachael and Stefanie begin to cry at the thought of having their hair cut off but most the girls are happy with the final result. Alex threw a temper tantrum at the thought of getting her hair cut, but she - like the others - was pleased with the final result.

The girls took part in a challenge for Jai Kudo glasses, to which the girls had to use their facial features to portray their set emotion, Stefanie excelled in this and won a set of Jai Kudo frames. They then later had to put together an outfit that showed their own personal style, in which Stefanie's glamour look is criticized, and Alex is again frustrated by her makeover. In the end, it is Charlotte that wins the challenge and is, coincidently, booked by the client for a future job.

The girls meet with TV star, June Sarpong to learn interview skills, and are watched undercover by two magazine journalists who praise Charlotte for being the most relaxed, Leanne for her story which "many would like to hear about" and Lisa for playing up to her androgynistic look. They say that Catherine and Martha were a 'breath of fresh air', but not interesting enough. Stefanie reveals during the interview that she once dated Lee Ryan, which sparks some snide comments from the other girls, with Alex saying they weren't interested by this fact at all.

This week the girls learn some new choreography with Supple, who has returned after training them in a previous episode. Alex and Aaron struggle with the dancing challenge, as do most of the girls except Stefanie who picked up the moves well. Yet, Stefanie did not win the challenge much to her disappointment, but was told she had a lot of potential. Ironically it was Alex who won, along with Rachael, Leanne and Catherine, who all performed their routine in a live concert.

The models face an acting challenge which includes a steamy kissing scene with guest actor Guy Burnet. The acting lesson serves as practice, as they later go on to film a commercial for jewellery, in which two girls are chosen as feature roles. It is revealed later at panel that the chosen girls are Alex and Catherine. The commercial causes a problem for Rachael as it involves moving around a set of fire, which she is affraid of, yet on set she seems to have no problem at all. This annoys Catherine and she confronts Rachael back at the house, in which Alex sides with Catherine. This then provokes Stefanie into defending Rachael, leading Catherine into calling her two faced. Charlotte then attempts to defend Rachael as she is angered by Catherine when she tells Rachael she doesn't like her facial expressions, Catherine retaliated stating Charlotte talks down to people. Leanne tries to calm things down and also defends Rachael, but is criticised by Catherine for being a 'clown'

The girls had to pose as different types of mannequines for their photoshoot.

First, the girls are put through a series of circus 'acts' including a tightrope competition and swinging from a trapeze, which Alex has trouble with due to her fear of heights. Later, Stefanie confronts Alex about how Alex speaks badly of her behind her back; a row ensues, leaving Alex and Stefanie's friendship in tatters. The next day, the girls are asked to model dresses on plinths in London's streets for an hour, changing their poses every five minutes; the task was won by Rachael, who got not only to keep her £1000 dress but also to invite two friends along for champagne (Charlotte and Stefanie), whereupon she was presented with a beautiful necklace worth in the region of £5000. Back at the house, Catherine and Alex decide to play a series of pranks on the three absent girls, including rubbing soap onto their toothbrushes, putting washing up liquid in Rachael's deodorant and leaving Stefanie a note 'reserving' her washing up but clearing everything else up. Before they return, Catherine's guilt gets the better of her and she disposes of the deodorant, but leaves the other pranks before pretending to sleep on the sofa with Alex. Upon the other girls' return, they confront Catherine and Alex, only for Alex to deny it was anything other than a 'harmless joke', as well as both the girls denying they touched the others' toothbrushes. Next, they are visited by Lisa herself, who reads them their Lisa-mail and presents them with 2 dresses each, whilst commenting Alex is not 'girly' enough. The girls then had to pose for beauty shots in Zandra Rhodes dresses, and under the designers direction, in the style of sporting events:

The girls start the week by attending a casting session with Sadie Frost and Jemima French, in which the girls are judged on their overall look and performance. The girls then view an African Tribal dance in which Lisa Snowdon is carried in at the end. Lisa informs the girls that whoever makes it through the next elimination, will continue the competition in South Africa.

In the penulimate episode of Cycle 4, the girls arive in South Africa and they participate in an African themed photoshoot. In the end one girl is sent home to the UK.

In the finale the girls do one last photoshoot with animals in the South African bush. Then, after one girl is eliminated, the girls participate in an African runway show and 'Britain's Next Top Model' is crowned.