Lüks uzay gemisi Avenue 5'ın kaptanı Ryan Clark, sahibi Herman Judd, geminin çalışanları ve yolcuları yaşanan arızanın ardından kötü bir haber alırlar.

Rav ve ekibi Nasa'dan bir yetkiliyle görüşür. Ryan, Cyrus adında bir mühendisle tanışır. Karen ise yolcuların sözcülüğünü üstlenir.

Avenue 5 personeli işleri yavaşlatır. Bu sırada Ryan, Karen'a yeteneklerini ön plana çıkarabileceği bir fırsat önerisinde bulunur.

Iris, Judd'ın itibarını korumak için bazı yolcuları lüks kamarasında ağırlar. Ryan ve Billie mühendislerle vakit geçirir.

Billie seeks her moment in the limelight after stepping in to help Ryan during the ship's newest crisis. Iris vets comedian Jordan Hatwal's material for the Halfway Home Party, which Judd has decided should go on as planned. Doug tries to get in the way of Mia's newfound sexual freedom.

Rav attempts to secure funds for a rescue mission, while on the ship the stress begins to show when what appears to be an oxygen leak is detected. Meanwhile Judd hits on a plan to beautify the ship's recently gained orbital ring.

Judd enlists Ryan to help charm Harrison Aimes, an uber-wealthy passenger who has a strange effect on Judd. Meanwhile, the passengers become transfixed by a divine image circling the ship and Rav deals with the fallout when the ship's moral quandary hits the media.

While Karen oversees an effort to jettison non-essential passenger items, Billie tries to teach an inattentive Ryan how to dock the ship. Matt learns of Judd’s plan to make the “ultimate sacrifice” by returning to Earth. Meanwhile, the passengers suspect all is not as it seems with the journey.

A search party commences for Matt, who’s in hiding with a guilty conscience – and the airlock codes. Iris questions Karen about her rumored affair with Ryan. Rav seeks an apology from Judd for ruining her life, as chaos ensues when a seat on a rescue shuttle suddenly becomes available. Season finale.