When the school trip vote between Nanette's suggestion of Ballet Russe or Angela's suggestion of "Monster Truck Rally" becomes a tie, Nanette proposes that they set up fund-raisers so whoever raises the most money gets to go on their suggestion. Angela, Gina, Johnny and Gordy decide that a "pet wash" is the best way to raise money.
Angela and her friends join a beginner's ice skating class only to find that not only has Nanette joined as well, but she already knows how to skate; and her show-off moves cause Angela to fall and break her arm.
Angela is worried because she did not come up with a topic for her rainforest project, until Mrs. Brinks falls ill, and is replaced by a substitute teacher named Miss. Geraldine "Gerry" Klump. Fortunately for Angela, Ms. Klump is shown to take a shine to her over Nanette.
Angela starts getting plagued with bad luck claiming they are all "accidents" despite Josephine Praline's insistence that the jinx is a natural result of not being "touched by an angel" and tries to persuade Angela into being nice to Nanette, despite Josephine herself not finding any good qualities in Nanette.
When Gordy expresses an interest in football, through horticulture, Coach Rhineheart enlists a few good men (Mark and Derek Anaconda) to help his son grasp the sport's finer points.
When Nanette is bedridden with the flu January and Karlene latch onto Angela who is given the job of leader of the spring fling contest and try to bribe her into picking them as her two helpers in order to remain "somebodies" rather than "nobodies".
Angela and Nanette each get new and nearly identical trench coats. When Angela gets Nanette's coat by mistake, she also finds herself in possession of Nanette's personal diary.
When Angela makes a mistake in a grammar game, saying, "I love Bob and Hot Chocolate" instead of "Bob and I love Hot Chocolate," Nanette immediately spreads a rumour that Angela likes "Bob."
Angela and Nanette become stuck together by bubble gum by their hair. When Nanette bitterly rejects the idea of having the gum hacked out of her perfectly curled hair, she and Angela have to put up with being stuck together.
Angela has been looking forward to joining her father and brothers on their annual fishing trip. However, when a new invention causes him injuries, Angela is stuck going on the trip with Mark and Derek who force her to do all of the dirty work and won't even let her fish.
Because of Baby Lulu, Angela gets poison ivy, scares off her friends, and misses "All-Creatures-Great-and-Small-Week" at school. The final straw comes when Lulu releases Angela's butterfly from captivity.
Angela finds herself trapped in the boys' bathroom.
Mr. Mapperson holds a contest to find a new face for his company's delivery truck. Though Angela and Nanette naturally compete the hardest out of everyone, are either of them who Mr. Mapperson truly has in mind?
Mrs. Brinks' class is learning multiplication. While Angela, with help from Gina, breezes through the lessons, Nanette struggles much to everyone's surprise, and Angela's delight. But the tables turn when Angela gets too cocky and Nanette enlists Gina's help with the promise of free food.
Angela has many qualities that none of her family members do, causing her to feel alienated from the Anaconda family, so she sets out to find who she really is related to.
Angela is so excited about wearing her new 'highway-worker-orange' windbreaker to school she completely forgets that it is St. Patrick's Day. According to Tapwater Springs' tradition you can pinch anyone not wearing green and when Angela arrives at school that morning everyone in her class can hardly wait until recess time to take advantage of Angela's forgetfulness.
Johnny and Angela get to run the school store. When Johnny becomes sick, Nanette steps in to fill his place, much to Angela's dismay.
Geneva's creative block is taking a toll on her skills as a mom. After commandeering Angela's homework (resulting in an F), she gives up art and devotes her time into being the perfect mother. But is all the fresh-squeezed orange juice, plastic wrapped furniture, and handmade clothes worth it if nobody is happy, especially Geneva?
Looking to confirm once and for all that Mr. and Mrs. Brinks are weekend nudists, Angela and her friends attempt to rebuild their treehouse higher and higher until it surpasses the fence and Gordy's topiary, thus assuring them the best seats in the house.
After Josephine teaches the class about Ash Wednesday, Nanette, wanting her memory to live on for eternity, suggests that the entire class participate in sacrificing something for forty days. While Angela gives up imagining things about other people, Nanette embarks on a superficial vow of poverty.
Angela goes on a chore strike when she realizes that her allowance is the lowest in town.
"Babble Balls" were all the rage in Tapwater Springs--until Angela had enough money buy one. Now she comes to learn from Nanette and the other kids that it's "Bug Thugs" which are currently 'da bomb'.
Gina Lash comes to Angela's house for a sleepover. However, things go out of plan when Angela's family starts paying more attention and idolism to Gina rather than Angela herself.
Josephine Praline reveals that her mother has agoraphobia. Angela tries to use this as an excuse to avoid not only school, but Mrs. Brinks's chalk erasers.
After Karlene fails to buy a hat made of real fur, January and Nanette instantly break off their friendship with her. A shocked Karlene then starts constantly leaning on Angela and co. and they invite Karlene into their gang. However, it is unclear whether Karlene is true friends with Angela or not.
Angela accidentally invents a new swinging craze. However, Nanette takes credit for it and names it the "Nanette Lock".