Cafasso and Sophie desperately search for their daughter Rosa, who went missing after leaving for Tunisia with her boyfriend. Meanwhile, Giulia and Antonio investigate a scam after receiving a package with unsavory contents.

A pasta factory closed due to protests over non-payment of wages raises suspicions of fraudulent bankruptcy, but the discovery of a body reveals a much more complex reality. The loss of a wallet will lead the Team on the trail of Barbara's rapists.

The discovery of the body of a sailor from the Kekova ship is linked to the theft of a painting by Luca Giordano. Tania receives harassment and confides in Giulia, while Cafasso accepts Sciacca's help to be close to his daughter Rosa.

A man is found dead in his apartment, apparently from cardiac arrest, but his criminal record raises suspicions. The medical examiner is threatened to change the cause of death. Meanwhile, Rosa, Cafasso's daughter, with Sciacca's support, begins to react to care and attention.

Antonio and Giulia, on duty at the wheel, discover a robbery in progress outside a bank. During a firefight, Giulia wounds one of the robbers, forcing them to flee without the loot. Stefano, affected by the loss of his wife, returns to work on Cafasso's advice, but risks his life at the first opportunity, highlighting difficulties in managing the trauma.

A special relationship has been established between Salvatore Sciacca and Rosa: he joined her on the pier of the port of Naples, but the atmosphere is ruined by the alarm of a fisherman who draws attention to a drifting boat with the body of Leonardo Nobis, hanged.

A phone call to Sant'Andrea communicates the death of the lawyer Raffaele Cunsolo, killed by a gunshot. A new killer drug is sweeping the streets and the Squad tries to catch those responsible.

The former usher Robertino, thanks to his reports, starts an investigation which reveals a cache of explosives. Meanwhile, the disappearance of Pasquale Fusco, Liwei's boyfriend and son of a Camorra, involves Anna and the Squad.

During the chase of a black Croma carrying drugs, Pasquale Fusco's body is thrown out of the moving car, revealing connections between the Camorra and the Chinese mafia. Pietro will have to face his first divorce hearing while Anna finds herself at a crossroads in her career.

The police officers at the Sant'Andrea police station must confront the reality of two young men with Down syndrome to solve a complex murder case. New officer Michelangelo Troisi joins the team.

Giobbe Covatta, spokesperson for AMREF, shows up at the Sant'Andrea police station to report the disappearance of a volunteer psychologist and three children in Sudan. Ponzese, a well-known fraudster, involves the police station in questionable affairs.

Barbara, terrified by an encounter with one of her rapists, runs to Sant'Andrea. Meanwhile, a charred body is found in a country lane with an engraved watch on his wrist. It will be a difficult investigation, which will involve the team emotionally and professionally.

Olympic champion Pino Maddaloni lends himself to fiction to tell the story of the recovery of a young woman in the Scampia neighborhood of Naples. The team investigates cases of girls involved in dangerous trips by unscrupulous adventurers.

The head of a small clan, an old acquaintance of Pietro's, is found murdered with a revolver shot. The investigation focuses on the cousin fighting with the victim for supremacy in the clan. A tip from the New York police will lead Antonio and Giulia on the trail of international trafficking.

During a prestigious cycling competition, a man commits suicide in the middle of the road. The team will discover the weaknesses, but also the strength, of young athletes willing to do anything to excel in their sport. The disappearance of a guest at Villa Orfea, the retirement home where Giulia's grandfather lives, will reveal disturbing truths.

Deputy Police Chief Cafasso finds himself at the center of a mysterious crime and Pietro is tasked with investigating without the knowledge of his boss and lifelong friend. The climate in the Sant'Andrea police station becomes tense. Meanwhile Antonio, following the death of a young worker at work, discovers a case of exploitation of harassed and underpaid workers.

Cafasso is investigated for the murder of the killer who was hunting him. Pettenella and Sciacca try to prove his innocence but discover truths that bring confusion and bitterness to the Sant'Andrea police station.

Amedeo Rotunno's body is found in the trunk of his car: the investigations reveal several lovers and a passion for horse racing. Meanwhile, Antonio Ramaglia's feelings of guilt grow, as he feels responsible for the betrayal of Michelangelo Troisi, a policeman colluding with the Camorra. The relationship between Pietro and Cafasso is now at a point of no return.

The lifeless body of Cristina, an aspiring dancer, is found near a car park: the girl was supposed to audition for a television program and suspicions focus on the world of entertainment. Tania becomes involved in a banking scam following the cloning of her ATM.

The Sicilian boss Carmelo Paterno seems to want to collaborate, but the team fears a double game: Walter and Sciacca, infiltrated in prison, are looking for evidence. A jeweler is killed and the briefcase he had strapped to his wrist mysteriously disappears.

A German woman reports the disappearance of her father, Helmut Strasser, and a man accuses himself of the murder of the eighty-four year old. The investigations of the Sant'Andrea police station raise doubts about the reliability of the confession. Meanwhile, an accident on the railway leads to an investigation into drug trafficking.

A man disappears after an Alcoholics Anonymous meeting he attends: the bitter discovery of the body by Walter, Anna and Sciacca leads to the start of very complicated investigations. Meanwhile, in a house outside the city, a man who trafficked clothing with Eastern countries is murdered with a stab in the back.

The gang war that periodically bloodies the streets of Naples has suddenly reignited with deaths and injuries on both sides. One of the very young boys hired by the Camorra, Tony Gallo, is found dead inside a car. Intense investigations begin by the Sant'Andrea police station, which is located right on the border between the areas controlled by the two rival clans.

A man is shot dead, shocking the community: investigations into the life of the well-known psychiatrist reveal a double life and connections with the Camorra. Meanwhile, a fire reveals a second murder, the surprising resolution of which falls to Inspector Guerra. Walter faces a difficult separation case.

A phone call to Sant'Andrea reports a raid by boys in the mood for pranks in the rundown alleys where prostitution is rampant. While Antonio, Giulia and the other agents collect the first testimonies. Demetrius discovers the slaughtered corpse of a prostitute: it is a case similar to another that occurred a week earlier. The whole team is busy searching for the killer.

Walter and Sciacca investigate the murder of a pharmacist killed by bladed weapon near a Circumvesuviana station. A charity match is planned at the stadium: a scenario in which, unexpectedly, Stefano will come to terms with his past.

Annamaria Pettenella's ex-wife asks the commissioner for help: her second husband, an esteemed lawyer from Piacenza, has disappeared. Meanwhile, an elderly professor attempts suicide by throwing himself in front of a bus: this time the track has to do with feelings, loneliness, friendship and love.

A woman comes out of a laundry holding her cyanotic son in her arms: at the hospital it is discovered that the child had swallowed a diamond. Meanwhile, the body of a woman is found in a car, who turns out to be a widow looking for a man who had disappointed her in love and had asked her to borrow money. The investigations proceed on the double trail of the widow and the diamonds.

The men of Sant'Andrea are busy solving the murder of a waiter at the Hotel Partenope. Different names, unknown people, a complicated mess for the men of the team to unravel. A cheerful birthday party ends up becoming a theater of violence and anguish.

A phone call to Sant'Andrea reports an apparent case of suicide: the investigation reveals a young vessel captain involved in dark affairs and particular friendships. The resolution of the case will have a strong repercussion on Cafasso's decisions, who feels the time has come to face Pietro again.