Daisy O'Brian is an ordinary girl who dreams of a singing career in musical comedy. Her parents are vampires, and according to her family tradition, she must decide whether to become a vampire or not on her 16th birthday. On that day, Daisy chooses to remain human to be with her love, Max, who is her neighbor and classmate. However, on that same day, a tragic accident changes her life forever. The doctor informs her parents that she is not going to survive. So, her parents decide to bite Daisy to save her, turning her into a vampire. This makes Vicente (her younger brother) the only mortal in the family. From that moment on, Daisy leads a double life full of risks, where she must attend a human school, hiding her true nature, while also going to vampire school and taking classes for newly turned vampires.