The cast of "Abbott Elementary" plays against the cast of "Hacks"; Kal Penn goes head-to-head with Erika Christensen.

Hip-hop group Salt-N-Pepa competes against the cast of the "The Proud Family"; the casts of "Bel Air" and "Saved by the Bell" compete.

The cast of "High School Musical: The Musical: The Series" compete against the cast of "Never Have I Ever"; Ron Funches competes against Meagan Good.

Vocal harmony group Boyz II Men, comic/talk show host Amber Ruffin, and actor/comics Joe Lo Truglio and Thomas Lennon compete for charity.

Rhys Darby and Jay Pharoah face off; Bachelor Nation goes head-to-head against each other to see who will reign supreme.

Kristin Chenoweth competes against Kathy Najimy; casts from reality shows "My Unorthodox Life" and "Summer House" compete.

Simu Liu goes head-to-head against Nathan Chen and his family; R&B singer Monica faces off against So So Def founder Jermaine Dupri.

Professional wrestlers Rey Mysterio and The Miz face off; former professional football player Kurt Warner goes head-to-head against former professional baseball player Orel Hershiser.

The Sharks from ABC's "Shark Tank" face off against the hosts from CBS's "The Talk"; comedians Natasha Leggero and Lauren Ash go head-to-head.

it's a showdown between NFLPA moms and their NFLPA player sons ; Joe Tessitore and Rob Riggle from ABC's "Holey Moley" go up against actress Kimberly Williams-Paisley and her family.

The cast of "Jackass" led by Johnny Knoxville and Jeff Tremaine, battle it out to see who will win the grand prize for their selected charities.