The Season 6 opener features a serial-rapist case in Reno.

Investigating the 1989 murder of a high-school student.

A Kentucky woman is found dead in the trunk of her car.

A business traveler is killed in his hotel room.

A 1997 murder in a California town is investigated.

The murder of an 8-year-old boy sparks a decades-long investigation.

The 1980 murder of a California businessman's wife is detailed.

A March 2000 murder in Anchorage is investigated.

The 1980 murder of a Colorado teenager is investigated.

The murder of a Wyoming teenager is investigated.

The murder of a Southern Illinois University student is investigated.

Investigating a daytime robbery at a nightclub in Arlington, Texas, that resulted in an employee's death.

An elderly couple are murdered in their Oregon home.