Sherri Shepherd kicks off her new daytime talk show and weighs in on the biggest pop culture headlines of the day.

Former talk show host Ricki Lake joins Sherri for her premiere week and tells us about her new podcast, Raised by Ricki.

Robin Thicke joins Sherri for her premiere week and previews the new season of The Masked Singer on FOX. Then, Derek Hough talks about the new season of Dancing with the Stars, now streaming on Disney+. Plus, Healthy Roots Dolls owner and CEO Yelista Jean-Charlestells Sherri about her toy company that empowers young girls.

Straight off the runways for New York Fashion Week – trailblazing supermodel Winnie Harlow is here! Then, famed fashion designer Sergio Hudson dressed former First Lady Michelle Obama, Vice President Kamala Harris, and Jennifer Lopez – to name a few. Now, straight from the New York Fashion Week runway, Sergio stops by to show off his ready-to-wear collection.

Sherri and her Girlfriends Talk It Out. Then, Chef Melba from the famed Melba’s restaurant in Harlem prepares some of Sherri’s favorite foods. Plus, a special performance from Sherri’s friend and former American Idol finalist, Trenyce.

Sherri shares her take on the latest pop culture headlines! Then, Oliver Hudson and Elodie Yung give us a sneak peek at the highly anticipated return of the FOX crime drama, The Cleaning Lady. Plus, Sherri’s Best Life Series continues with motivational speaker, Jen Hatmaker

Nicole Scherzinger joins Sherri to dish about the new season of The Masked Singer on FOX. Then, Brittney Levine shows us the latest viral trends on TikTok! And, the hilarious Eleanor Kerrigan drops into Sherri’s Laugh Lounge!

The “Mother of Black Hollywood”, Jenifer Lewis, tells Sherri about her highly anticipated new book, Walking in My Joy and shares her hilarious take on what’s happening in the world today.

It’s a family affair when Danny DeVito and his daughter Lucy stop by to tell Sherri about their animated comedy, Little Demon on FXX. Then, Donny Osmond tells Sherri about his return to Las Vegas, for his first-ever solo residency at Harrah’s.

Entertainment mogul Tyler Perry tells us about his new Netflix film, A Jazzman’s Blues! Then, entertainment reporter Jasmine Simpkins gives us a sneak peek at this fall’s highly anticipated movies.

Sherri shares her take on the latest pop culture headlines! Then, Mickey Guyton performs her new song, “Somethin’ Bout You” and chats with Sherri. Plus, Sherri’s Best Life Series with celebrity nutritionist, Dr. Ro!

Sherri’s bff Niecy Nash-Betts, gives us a sneak peek at her highly anticipated new ABC drama, “The Rookie: Feds”. Then, the hilarious Cocoa Brown drops into Sherri’s Laugh Lounge!

Actress Amirah Vann tells Sherri about her new film, ‘A Jazzman’s Blues’ currently streaming on Netflix. ​ Celebrity Chef Carla Hall mixes up some fall desserts and tells Sherri about the Halloween Baking Championship airing on Food Network. Plus, Sherri weighs in on the latest pop culture headlines!

Frozen’s Elsa and Tony Award-winner Idina Menzel, and her sister Cara Mentzel tell Sherri about their new lyrical picture book “Loud Mouse”.

Alfonso Ribeiro hits the couch to dish about the new season of Dancing with the Stars on Disney+.

Sherri kicks off the week by giving her hilarious take on the headlines! Then, the iconic Tyra Banks stops by to talk about hosting the new season of “Dancing with the Stars” on Disney+.

Tamera Mowry-Housley joins Sherri to talk about her new memoir, “You Should Sit Down for This.”

Star Jones sits down with Sherri to discuss her return to Daytime TV as the new Host and Judge of “Divorce Court.”

Sherri offers her hilarious take on the headlines!

Actress and host Tori Spelling stops by to talk to Sherri about hosting MTV’s new dating series, “Love at First Lie: Who’s a Couple and Who’s a Con?”

Actress Sharon Horgan stops by to discuss her Apple TV+ series, “Bad Sisters.” Then, actor Daniel Ezra sits down with Sherri to talk about the fifth season of “All American” premiering on The CW. Plus, Sherri gives her hilarious take on the latest headlines!

Emmy winning host & comedienne Loni Love talks being a judge on Criss Angel’s “Magic With the Stars.” Then, former “American Idol” contestant and singer, Pia Toscano, performs a single from her debut album “I’m Good”. Plus, Sherri delivers her hilarious take on the latest headlines!

In a daytime TV exclusive, former “The Real” host Adrienne Bailon Houghton and her husband, Grammy winner Israel Houghton discuss having their first child together via a surrogate. Plus, Israel performs a song from his newly released Gospel album.

Oscar-winning actress Geena Davis tells us about her new memoir, “Dying of Politeness: A Memoir by Geena Davis.” Plus, star of the Bravo franchise “Married to Medicine,” Quad Webb, is here to cook up something delicious with Sherri while discussing her debut cookbook, “Cooking with Miss Quad.” And of course Sherri offers her hilarious take on the headlines!

Tony Award winner, Michael R. Jackson chats with Sherri about his acclaimed musical “A Strange Loop!”

Actor John Lithgow stops by to discuss the one man show he’s directing, “Everything’s Fine.”

New York real estate mogul and “Shark Tank” judge, Barbara Corcoran, joins Sherri to talk about all things business.

Sherri delivers her hilarious take on the latest headlines!

Pop culture gurus, Bevy Smith, Tammy Pescatelli & Jacquie Reid join Sherri’s “Talk it Out Panel” to weigh in on the latest trending stories.

The stars of “Big Shot” on Disney+, John Stamos & Sophia Mitri Schloss sit down with Sherri to talk about season 2 of the series.