SNL alums Taran Killam and Rob Riggle face off in an epic battle; LGBTQ icons past and present collide as Culture Club’s Boy George faces off with “Orange Is the New Black” star Laverne Cox.

Kermit and Pepe go up against Miss Piggy and Beaker in the greatest (and only) Muppet rap battle of all time; three castaways from “Lost,” Daniel Dae Kim, Josh Holloway and Harold Perrineau, have a not-so-friendly mainland reunion.

The Vampire Diaries star Kat Graham takes a bite out of Shameik Moore. Can this Spider-Man fight back? Then it's a standup standoff when two comedy giants, Nikki Glaser and Brad Williams, start throwing punch lines.

Basketball star Lonzo Ball tries to dunk on the king of auto-tune, T-Pain; friends become foes as a slimmed-down Kevin Smith goes head to head with Jason Mewes; Jay and Silent Bob will never be the same.

Drop The Mic is at Universal Orlando Resort in Orlando, FL. R&B singer NE-YO battles Mike Colter to see if he's as tough as Luke Cage. Then it's a pop star party when Christina Milian and Ashlee Simpson see which voice can deal more pain.

DTM leaves Universal Orlando Resort with a bang! Jack and Kelly Osbourne take sibling rivalry to the next level in a family feud rap battle. Then Spice Girl Mel B spars with La La Anthony when there's only room for one diva on stage.

Funnyman Ron Funches battles Raven-Symone, who may look harmless, but is a beast with the mic. Then it's a battle of boy band legends with NSync's Joey Fatone and NKOTB's Joey McIntrye pushing their friendship aside to go one-on-one.

Straight Outta Compton's Jason Mitchell channels Eazy-E against American Horror Story's chilling Adina Porter. Then 90's TV teens are grown up as Married With Children's David Faustino and Blossom's Joey Lawrence duke it out with bars.

Wrestling superstars Rusev and Lana hunt shark Mark Cuban to see who's the baddest beast; tag-team champs The New Day jump in the ring with iconic soul singers SWV in a no-holds-barred grudge match.

Glee" stars Amber Riley, Harry Shum Jr. and Becca Tobin battle former castmates Kevin McHale, Jenna Ushkowitz and Heather Morris; Jason Biggs and Eddie Kaye Thomas of "American Pie" serve up slices of lyrical hurt.