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1. Bölüm When a commuter ship capsizes, the ED finds itself under water as the staff struggles to treat the influx of new patients and deal with bold new employees taking charge.
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2. Bölüm Lenox continues to rankle Archer as the two tackle their new roles. Ripley faces possible suspension over what really happened to Pawel. Goodwin is forced to make layoffs.
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3. Bölüm Asher treats a woman whose undiagnosed condition threatens the lives of both her and her unborn child. Goodwin receives a chilling message while battling the hospital higher-ups.
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4. Bölüm A familiar face returns to the ED. Ripley and Charles treat a woman with a rare disorder. Frost suspects that his patient's father is lying about his daughter's condition.
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5. Bölüm Halloween chaos takes over the ED. Asher helps a pregnant woman with an autistic son. Charles clashes with Nurse Jackie on a psych case.
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6. Bölüm Chicago P.D. steps up Goodwin's security after she's threatened online by a former employee. Archer and Frost treat victims from a disciplinary camp injured during a rockslide. Maggie gets roped into delivering a high schooler's baby.
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7. Bölüm Ripley and Frost uncover shocking information that conflicts with their patient's DNR. Asher facilitates an unexpected reunion. The tension between Archer and Lenox comes to a head.
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8. Bölüm Goodwin's troubles persist. Charles clashes with his former resident over a depressed patient. Lenox and Ripley treat a car accident victim who recently reunited with his college sweetheart.
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9. Bölüm The team fights to save the life of one of their own. Frost and Abrams butt heads with their patient. Asher helps a religious young woman with an ectopic pregnancy.
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10. Bölüm An army of surgeons prepares to separate conjoined twins. Asher reconnects with someone from her past. Archer treats a tyrannical boss with a heart problem.
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11. Bölüm Following the subway tunnel collapse, Ruzek and Kidd treat injured passengers and track down the missing offender. Archer and Frost perform a life-saving amputation.
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12. Bölüm Goodwin struggles with the psychological aftermath of her attack. Ripley treats a patient with helicopter parents. An ED staffer makes a mistake that may cost them their job.
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13. Bölüm Lenox's mentorship is put to the test. Asher helps a religious young woman with an ectopic pregnancy. Ripley's self-destructive behavior continues to escalate.
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14. Bölüm Gaffney gets a surprise visit from a National Accreditation Board of Hospitals representative. Asher and Naomi search for the cause of a young girl's infection. Lenox and Frost work together to save the victim of an accidental shooting.
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15. Bölüm Ripley struggles to rescue a woman and her daughter trapped in an abandoned well. An old friend from Frost's TV days shadows Maggie. Asher discovers an extremely rare condition in her patient's ultrasound.
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16. Bölüm When her former patient returns to Med, Goodwin learns that time doesn't heal all wounds. Frost and Charles treat a patient struggling with his sexuality. Lenox and Abrams work to save a woman who has been in a coma for 20 years.
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17. Bölüm Charles and Archer treat a heart transplant patient who believes his new heart doesn't want to be in his body. Lenox takes a personal day. Asher discovers a mass on a pregnant woman's ovary.
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18. Bölüm Asher makes a tough call to save a life. Frost and Ripley treat a young boy with a snake bite. Archer gives Naomi a patient to handle on her own on her last day in the E.D.
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19. Bölüm Maggie and Goodwin's friendship is tested as tensions rise during the nurses' union's negotiations with the hospital. Ripley and Archer treat a skateboarder struck by an emergency vehicle. Frost helps a young boy abandoned by his mother.
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20. Bölüm The hospital faces a staffing crisis as the nurses stage a sick-out. Archer and Frost bet on who can discharge their patients first. Charles' distrust of a patient complicates his treatment.
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21. Bölüm Maggie and Frost fight to get a pair of lungs for a young cystic fibrosis patient. Asher learns whether she can become a surrogate. Ripley and Morris treat a tech billionaire's daughter as she battles leukemia.
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22. Bölüm Goodwin is tasked with enforcing difficult cuts to hospital personnel. Charles' daughter is hospitalized after a car accident. A transplant patient makes a life-changing decision.