Seth Rogen shared on “The A24 Podcast” why Anne Hathaway left the 2007 film “Knocked Up.” Rogen noted that Hathaway decided not to participate in Judd Apatow's classic comedy, citing the graphic birth scenes as the reason. He expressed that Hathaway felt those scenes did not align with her image.

Olivia Wilde, who appeared on the show alongside Rogen, mentioned that she auditioned for the female lead in the film but did not get the role. Hathaway's departure was a surprising development for the film crew. Rogen discussed that he understood the reasoning behind Hathaway's decision and talked about its impact on the film.

“Knocked Up” received significant attention upon its release and has secured an important place in the comedy genre. Although Hathaway's exit changed the dynamics of the film, Rogen and Heigl's performances still led to its successful reception by audiences. This incident can also be seen as an example of actors' sensitivity to content in projects in Hollywood.