On its second mission, the new "Tatort" team has to solve a particularly delicate criminal case, because an extremely spicy situation becomes fatal for those involved: while the easy-going Roman Kraus and the escort girl he paid, Mirjam, are partner-swapping with the prominent couple Peter and Helene Pollak, Roman's wife, a well-known pharmaceutical researcher, is murdered and a valuable scientific discovery is stolen. All evidence found at the crime scene points to Roman Kraus as the perpetrator, but Chief Inspector Eisner believes that Kraus is innocent.
